Glutathione (reduced) is found throughout the body, mainly in the liver, kidneys, and lining of the lungs and intestines.
It is the body’s main endogenous antioxidant and plays a central role in maintaining the REDOX state of every cell.
What are the benefits of acetylglutathione?
Glutathione is a tripeptide (i.e., made up of three amino acids), it is not well absorbed by the gut, has a short half-life in plasma, and it is unclear whether it can be transported into cells in large quantities.
When ingesting glutathione, the body must break down most of it into its constituent amino acids (cysteine, glutamate, glycine) before it can be absorbed into the blood.
Even if partially intact GSH enters the bloodstream, to be absorbed by cells, it must be converted into GSH through decomposition and resynthesis, and metabolic and enzymatic disorders in the body can affect these processes.
Acetyl glutathione is stable in plasma and can be directly absorbed by cells. The sulfhydryl part of the peptide contains an acetyl group. Within the cell, acetyl groups are removed to replenish GSH for the mitochondria to do their job.
The role of acetyl glutathione
As an antioxidant, it can scour free radicals and reduce the damage of cells caused by oxidative stress.
It can promote the detoxification function of the liver and reduce the damage of poisons to the body. Acetyl glutathione is often used to prevent liver disease, cardiovascular disease, and immune system diseases.
Can promote collagen synthesis, increase skin elasticity, reduce the appearance of wrinkles and fine lines. It also has the effect of regulating skin pigmentation, which can reduce dark spots, freckles and other color spot problems. Acetyl glutathione also provides the moisture the skin needs to keep it moist.
Acetyl glutathione is also involved in maintaining intracellular REDOX balance and influences many biochemical reactions. It can regulate enzyme activity and affect protein structure and function.