For thousands of years, people have never given up the dream of immortality, we believe in evolution still have a new want to break the laws of nature, and there are many scientists addicted to this research. Yes, that’s NMN.
What is NMN?
NMN is a bioactive nucleotide that slows down aging.
However, there are actually two irregular forms of NMN, α and β.
Its molecular weight and structure are basically the same, but the arrangement is reversed.
NMN is the precursor of NAD+, which cannot play a role alone, and its function is reflected by converting into NAD+ in the human body, so as to achieve anti-aging.
So we need to understand what NAD+ does in the human body first.
NAD+ (nicotinamide adenine dinucleotide) is a coenzyme that maintains the normal life activities of cells and is essential for energy metabolism, the immune system, and material metabolism, including cellular energy production and DNA repair.
NAD+ function
Strengthen the immune system
Promotes cell energy production
Helps repair DNA
Activate Sirtuins all longevity proteins
As we age, NAD+ levels gradually decline, leading to decreased energy levels and physical function.
Low NAD+ levels can cause skin aging, decreased energy, less energy than before, decreased muscle levels, and can cause a variety of diseases such as cardiovascular disease and neurodegenerative diseases.
If we get enough NAD+, many of the body’s functions start to look young again.
Supplementing NMN helps to increase NAD+ levels, thereby delaying the aging process.
The main functions and effects of NMN
01 Greatly improve mitochondrial function
Mitochondria are the main “power stations” of the cell, and the vast majority of metabolic activities in the cell use the energy stored in ATP.
Mitochondria store energy from food in ATP for subsequent metabolic activity.
Supplementing NMN can improve the activity of Sirts enzyme dependent on NAD+, remove excessive acetylation modification of mitochondrial proteins, regulate the activity of downstream metabolic enzymes, greatly improve the ability of mitochondria to provide energy, “nourish” a variety of tissues and organs, and resist aging.
Indeed, studies have found that supplementing NMN can improve the mitochondrial function of cardiomyocytes, improve the contractility of cardiomyocytes, and improve heart failure.
02 Improved DNA repair function
The double helix structure of DNA has a strong ability to self-repair, when one strand is damaged, the other strand will act as a template to quickly repair.
If both strands of DNA break at the same time, and the template lost, the cell initiates an emergency repair program to repair the DNA damage.
As we age, DNA strands become more and more likely to break, and these damages accumulate with age, eventually leading to aging.
Repairing DNA damage is central to reversing aging.
03 can promote a variety of stem cell proliferation
Stem cells are a kind of cells with self-renewal ability and differentiation potential.
Stem cells proliferate continuously, some of them remain dry and maintain self-renewal;
The other part differentiated and replenishes various tissues and organs.
NMN can provide supplementary energy for a variety of stem cells, activate proliferation-related pathways, and promote the proliferation of a variety of stem cells.
04 Reduce oxidative stress response
Oxidative stress refers to the imbalance of oxidation and anti-oxidation in the body, which tends to oxidation, resulting in neutrophil inflammatory infiltration, increased protease secretion, and the production of a large number of oxidative intermediates.
Oxidative stress a kind of negative effect produced by free radicals in the body, and almost all cells in the human body easily damaged by oxidative stress.
Many of the health problems associated with aging, such as Alzheimer’s disease, impaired blood sugar and heart function, have linked to it.
Studies at home and abroad have found that NMN supplementation can improve cognitive function, reduce the level of myocardial mitochondrial oxidative stress, and weaken the oxidative stress state in nerve cells.
Supplementing with NMN can directly increase the level of NAD + in the body, thus counteracting the natural decline that occurs with age.
Application of NMN
GSHWORLD has its own NMN brand, based on the health industry with a unique formula, each capsule contains high-purity essence NMN, natural metabolites α-ketoglutaric acid and quercetin, effectively improve the concentration level of NAD+ in the body, stabilize and extend telomere length, and has three synergistic health care, including repair, anti-inflammatory, regeneration and young state. It is a scientific, safe, effective and high-quality functional supplement.